Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. 75(7): p. 688-94. Article Clin Radiol, 2014.
Google Scholar. I feel grateful to be a postdoc mentor, knowing that the mentor-trainee interaction not only leads to scientific breakthroughs but also brings fresh enthusiasm to my research group and challenges me to grow as a scientist. Pathol Int, 2010. 51(4): p. 562-6. Scientists know that the work they’re doing has a profound impact on people’s lives. Histopathology, 2012. Historically, Notch has been most thoroughly studied as an arbiter of cell-to-cell communication that mediates binary cell fate decisions of dividing progenitors. Dig Liver Dis, 2011. Lemoinne, S., et al., Simple Magnetic Resonance Scores Associate With Outcomes of Patients With Primary Sclerosing Cholangitis. Using novel antibodies that selectively inhibit the Notch ligands Jag1 or Jag2, we discovered that Jag blockade dramatically alters cell fate in the epithelial layer of mouse lung airways. 20(1): p. 143-58. Nilsson, H., et al., Dynamic gadoxetate-enhanced MRI for the assessment of total and segmental liver function and volume in primary sclerosing cholangitis. Genentech takes the health and safety of our patients, customers, employees and local communities very seriously, and we are actively responding to the global COVID-19 pandemic. Eur Radiol, 2016. Contributing to a research community that combines the philosophy of “following the science” with a stellar track record of converting discoveries into medicines has proven extremely motivating. The postdoc program is central to the intellectual vitality of Genentech Research, providing license to pursue compelling basic research questions and actively engage at the cutting edge of the larger scientific community. In this study, change of soil profile water content, seepage water, precipitation, and evapotranspiration were determined directly from 10‐min lysimeter data from 2011. 60(3): p. 167-74. Dig Dis Sci, 2007. 51(1): p. 149-55. Following academic training with a research focus on RNA biochemistry, I made the big decision to decline academic opportunities, switch fields, and begin a career in biotech. Durand, F. and D. Valla, Assessment of the prognosis of cirrhosis: Child-Pugh versus MELD. Google Scholar. After negotiating the ups and downs at a couple of early-stage companies, I embraced the chance in 2005 to join Genentech and lead a collaborative effort to target the Notch signaling pathway. Kim, W.R., et al., A revised natural history model for primary sclerosing cholangitis. CAS 42 Suppl(1): p. S100-7. Article J Hepatol, 2009. Keller, S., et al., Prospective comparison of diffusion-weighted MRI and dynamic Gd-EOB-DTPA-enhanced MRI for detection and staging of hepatic fibrosis in primary sclerosing cholangitis. Rudolph Ring. Clin Liver Dis, 2016. PubMed Article PubMed Monitoring tomato root zone water content variation and partitioning evapotranspiration with a novel horizontally-oriented mobile dielectric sensor. We're looking for smart passionate people to join us. Working off-campus? Olsson, R., et al., High-dose ursodeoxycholic acid in primary sclerosing cholangitis: a 5-year multicenter, randomized, controlled study. Hepatology, 2007. Liver Int, 2018. Frydrychowicz, A., et al., Gadoxetic acid-enhanced T1-weighted MR cholangiography in primary sclerosing cholangitis. Hinrichs, H., et al., Functional gadoxetate disodium-enhanced MRI in patients with primary sclerosing cholangitis (PSC).
Fifty-one patients (M/F 37/14, mean age 41 years) with PSC who underwent MRI and liver histopathology were included in this IRB-approved retrospective study. - 206.54.183.116. FIB-4 index, Child–Pugh, MELD, Mayo Risk, APRI, and alkaline phosphatase demonstrated good to excellent performance for advanced PSC stage (AUCs 0.672–0.915, p < 0.045). J Gastroenterol Hepatol, 2016. 39(4): p. 879-86. https://doi.org/10.1007/s00261-019-02366-9, DOI: https://doi.org/10.1007/s00261-019-02366-9, Over 10 million scientific documents at your fingertips, Not logged in Enter your email address below and we will send you your username, If the address matches an existing account you will receive an email with instructions to retrieve your username, I have read and accept the Wiley Online Library Terms and Conditions of Use. PubMed High-resolution estimation of the water balance components from high-precision lysimeters. Gut, 2002. 36(2): p. 151-6. Before moving to Jason's current city of Tijeras, NM, Jason lived in Albuquerque NM and Wells NV. Please check your email for instructions on resetting your password. Get the latest New Orleans, LA Local News, Sports News; US breaking News. CAS Acute Jag blockade induced a rapid and near-complete loss of secretory club cells, with a concomitant gain in ciliated cells, under homeostatic conditions. Abdominal Radiology © 2020 Genentech, USA Inc. All rights reserved. The water balance of a certain soil profile in a certain time interval is subjected to changes of soil water content within the respective profile, and fluxes at its upper and lower boundary. and M.S. Generally, the utilized lysimeter facility and the specific data management provided sound water‐balance components with high accuracy and temporal resolution, respectively. Stanich, P.P., et al., Alkaline phosphatase normalization is associated with better prognosis in primary sclerosing cholangitis. https://www.gene.com/scientists/our-scientists/chris%20-siebel. CAS PLoS One, 2018.
Schauspieler und Kabarettist Manuel Rubey und Architektin Stefanie Nolz sind seit Jahren ein Paar und haben zwei Töchter. J Hepatol, 2002. Crop water use under Swiss pedoclimatic conditions – Evaluation of lysimeter data covering a seven-year period. Impacts of climate and management on water balance and nitrogen leaching from montane grassland soils of S-Germany. Petrovic, B.D., et al., Correlation between findings on MRCP and gadolinium-enhanced MR of the liver and a survival model for primary sclerosing cholangitis. However, using separately measured precipitation data may cause implausible (negative) evapotranspiration. This site is intended for US residents only. Eur Radiol, 2019. Eur J Gastroenterol Hepatol, 1995. Gastroenterology, 2014. 22(8): p. 689-98. Lindstrom, L., et al., Association between reduced levels of alkaline phosphatase and survival times of patients with primary sclerosing cholangitis. PubMed To assess the diagnostic performance of magnetic resonance imaging (MRI) compared to blood tests and clinical scoring systems for the evaluation of histopathologic severity in patients with primary sclerosing cholangitis (PSC). 31(6): p. 1184-90. PubMed PubMed Central
J Magn Reson Imaging, 2014. Hepatology, 2014. Abdom Radiol (NY), 2017. 43(4): p. 309-13.
PubMed Central PubMed Such precise manipulation of the pathway not only shows promise in disease indications such as cancer, regenerative medicine and immunology but also enables discoveries of how Notch functions in adult mammalian biology. Liver Int, 2010. Comparison of simple rain gauge measurements with precision lysimeter data. Diseases characterized by excess mucus secretion provide a compelling entrée but we suspect that there may be broader implications. Two radiologists independently graded the severity of biliary abnormalities on magnetic resonance cholangiopancreatography (MRCP) using a standardized scoring system, parenchymal enhancement, and diffusion-weighted imaging (DWI) signal. Article Histopathology was assessed using a modified Nakanuma’s scoring system. Many factors combine to make Genentech a fantastic place to pursue postdoctoral research. In the past, Jason has also been known as Jason A Nolz, Jason Al Nolz, Jason P Nolz, Jason Philip Nolz and Jason S Nolz. Immediate online access to all issues from 2019. Portmann, B. and Y. Zen, Inflammatory disease of the bile ducts-cholangiopathies: liver biopsy challenge and clinicopathological correlation.
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